Table 2 Incidence of all types of stroke, hemorrhagic stroke and ischemic stroke

From: Effects of a benidipine-based combination therapy on the risk of stroke according to stroke subtype: the COPE trial

 

Total (n=3293)

Benidipine plus ARB (n=1110)

Benidipine plus BB (n=1089)

Benidipine plus TD (n=1094)

P-value Log-rank

All types of stroke

56 (4.7)

17 (4.2)

27 (7.0)

12 (3.0)

0.0326

Hemorrhagic stroke

19 (1.6)

8 (1.9)

9 (2.5)

2 (0.5)

0.1001

 Intracerebral hemorrhage

17 (1.4)

6 (1.4)

9 (2.5)

2 (0.5)

0.1035

 Subarachnoid hemorrhage

2 (0.2)

2 (0.5)

0 (0)

0 (0)

0.1444

Ischemic stroke

30 (2.5)

9 (2.2)

15 (3.9)

6 (1.5)

0.1046

 Lacunar stroke

13 (1.1)

5 (1.2)

6 (1.5)

2 (0.7)

0.3606

 Large-artery stroke

7 (0.6)

0 (0)

5 (1.5)

2 (0.5)

0.0608

 Cardioembolic stroke

3 (0.3)

1 (0.2)

2 (0.5)

0 (0)

0.3601

 Unknown ischemic type

7 (0.6)

3 (0.7)

2 (0.5)

2 (0.5)

0.8879

Transient ischemic attack

7 (0.6)

0 (0)

3 (0.7)

4 (1.0)

0.1497

  1. Abbreviations: ARB, angiotensin receptor blocker; BB, β-blocker; TD, thiazide diuretic.
  2. Data are shown as incidence number (per 1000 person-years).