Table 3 Factors contributing to changes in blood pressure at 1 week after the earthquake

From: Blood pressure elevation in hemodialysis patients after the Great East Japan Earthquake

(A) Pre dialysis

 

Change in systolic blood pressure

Change in diastolic blood pressure

  

Multivariate

 

Multivariate

 

Univariate

R2=0.09

Univariate

R2=0.02

 

r

P-value

B

P-value

r

P-value

B

P-value

Age (years)

0.10

0.06

 

NS

0.08

0.12

 

NS

Gender (male)

−0.12

0.03

 

NS

−0.06

0.18

 

NS

Dialysis vintage (years)

−0.03

0.32

 

NS

−0.07

0.15

 

NS

Hypertension

−0.11

0.05

 

NS

−0.12

0.33

 

NS

Diabetes

−0.05

0.23

 

NS

−0.01

0.42

 

NS

Hyperlipidemia

0.03

0.31

 

NS

0.05

0.22

 

NS

Cardiovascular disease

0.07

0.15

 

NS

0.07

0.13

 

NS

Pre-dialysis systolic/diastolic blood pressure at baseline (mm Hg)

−0.33

<0.01

−0.29

<0.01

−2.00

<0.01

 

NS

Pre-dialysis heart rate at baseline (per min)

−0.07

0.34

 

NS

−0.05

0.42

 

NS

RAS-I

−0.15

0.01

 

NS

−0.15

0.01

−0.15

0.03

CCB

−0.02

0.38

 

NS

−0.05

0.20

 

NS

α-Blockers

−0.19

<0.01

−0.15

0.03

−0.16

<0.01

 

NS

β-Blockers

−0.09

0.08

 

NS

−0.09

0.09

 

NS

Diuretics

−0.09

0.09

 

NS

−0.01

0.41

 

NS

DRI

−0.08

0.11

 

NS

−0.12

0.03

 

NS

(B) Post dialysis

 

Change in systolic blood pressure

Change in diastolic blood pressure

   

Multivariate

  

Multivariate

 

Univariate

R2=0.10

Univariate

R2=0.03

 

R

P-value

B

P-value

r

P-value

B

P-value

Age (years)

−0.01

0.39

 

NS

−0.01

0.40

 

NS

Gender (male)

−0.01

0.43

 

NS

−0.05

0.22

 

NS

Dialysis vintage (years)

−0.005

0.47

 

NS

0.02

0.38

 

NS

Hypertension

0.003

0.48

 

NS

−0.005

0.47

 

NS

Diabetes

−0.04

0.28

 

NS

0.002

0.48

 

NS

Hyperlipidemia

0.001

0.49

 

NS

0.03

0.29

 

NS

Cardiovascular disease

0.04

0.25

 

NS

0.02

0.35

 

NS

Post-dialysis systolic/ diastolic blood pressure at baseline (mm Hg)

−0.25

<0.01

−0.30

<0.01

−0.18

<0.01

−0.19

<0.01

Post-dialysis heart rate at baseline (per min)

0.06

0.38

 

NS

0.02

0.38

 

NS

RAS-I

0.03

0.33

 

NS

−0.01

0.43

 

NS

CCB

0.11

0.05

0.18

0.01

0.05

0.20

 

NS

α-Blockers

−0.03

0.29

 

NS

−0.11

0.05

 

NS

β-Blockers

0.01

0.39

 

NS

−0.10

0.06

 

NS

Diuretics

−0.06

0.18

 

NS

−0.06

0.17

 

NS

DRI

−0.02

0.37

 

NS

−0.02

0.35

 

NS

  1. Abbreviations: CCB calcium channel blocker; CVD, cardiovascular disease; DRI, direct renin inhibitor; RAS-I, renin–angiotensin inhibitor.
  2. Multivariate logistic regression analysis included pre-dialysis changes in systolic (or diastolic) blood pressure at 1 week (A) and post-dialysis changes in systolic (or diastolic) blood pressure at 1 week (B) as dependent variables. Adjusted potential confounding variables comprised age, gender, dialysis vintage, hypertension, diabetes, hyperlipidemia, CVD, pre- (or post-) dialysis systolic (or diastolic) blood pressure at baseline, pre- (or post-) dialysis heart rate at baseline, RAS-I, CCB, α-blockers, β-blockers, diuretics and DRI.