Figure 1 | Hypertension Research

Figure 1

From: Role of gap junctions in the contractile response to agonists in the mesenteric artery of spontaneously hypertensive rats

Figure 1

The electrical coupling of in-situ and dispersed mesenteric artery (MA) vascular smooth muscle cells (VSMCs) of spontaneously hypertensive rats (SHRs) and Wistar-Kyoto (WKY) rats. (a) Whole-cell current traces induced by voltage steps from the holding potential −40 mV in 20 mV increments on in-situ and dispersed VSMCs. (b) Time-scale-expanded presentation of the initial part of a (some traces omitted for clarity), showing that a single-term exponential function (red lines between two cursors) fitted poorly (r<0.90) with the current transients (black thin line) in in-situ VSMCs, but fit well (r>0.98) in dispersed VSMCs. ‘C’ and ‘τ’ membrane input capacitance and time constant for the bottom trace.

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