Table 1 Baseline cardiovascular parameters of control and L-NAME hypertensive rats

From: Enantioselective pharmacokinetics and cardiovascular effects of nebivolol in L-NAME hypertensive rats

Parameter

Control rats (n=18)

L -NAME rats (n=18)

Cardiovascular parameters

 MAP (mm Hg)

105±3

132±2*

 HR (b.p.m.)

348±8

341±6

Blood pressure variability

 s.d. (mm Hg)

3.97±0.26

5.27±0.26*

 VLF variability (mm Hg2)

11.7±1.0

22.5±1.4*

 LF variability (mm Hg2)

8.9±0.7

15.3±1.1*

 HF variability (mm Hg2)

2.5±0.3

3.2±0.3

 LF/HF ratio

3.79±0.21

4.92±0.28*

  1. Abbreviations: HF, high frequency; HR, heart rate; MAP, mean arterial pressure; LF, low frequency; VLF, very low frequency.
  2. *P<0.05 vs. control rats by Student’s t-test.
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