Table 2 Associations of CHADS2 and CHA2DS2-VASc scores with risks of ischemic stroke and bleeding events

From: CHADS2 and CHA2DS2-VASc scores as bleeding risk indices for patients with atrial fibrillation: the Bleeding with Antithrombotic Therapy Study

 

Ischemic stroke: model 1

Ischemic stroke: model 2

Bleeding: model 1

Bleeding: model 2

 

HR

95% CI

P-values

HR

95% CI

P-values

HR

95% CI

P-values

HR

95% CI

P-values

CHADS 2

 Per 1−category increase

1.76

1.04–3.38

0.033

1.76

1.03–3.38

0.037

1.10

0.71–1.80

0.679

1.12

0.72–1.84

0.623

 Per 1−point increase

1.35

1.05–1.74

0.019

1.33

1.03–1.73

0.025

1.04

0.81–1.32

0.776

1.05

0.82–1.34

0.717

CHA 2 DS 2 -VASc

 Per 1−category increase

2.20

0.91–8.46

0.087

2.18

0.89–8.43

0.096

1.20

0.63–2.85

0.622

1.17

0.61–2.82

0.668

 Per 1−point increase

1.23

1.01–1.51

0.043

1.21

0.99–1.49

0.059

1.10

0.90–1.34

0.362

1.11

0.90–1.36

0.328

  1. Abbreviations: CI, confidence interval; HR, hazard ratio.
  2. Model 1: adjusted for antithrombotic medication.
  3. Model 2: adjusted for antithrombotic medication, neoplasm, liver cirrhosis, hypercholesterolemia, current smoking and alcohol consumption.
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