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Figure 1

From: Decreased perivascular CGRP-containing nerves in Otsuka Long–Evans Tokushima Fatty rats with insulin resistance and hypertension

Figure 1

Vasoconstrictor responses to perivascular nerve stimulation (PNS) (a and b; 4–12 Hz) and injections of noradrenaline (NA) (c and d; 5 and 10 nmol) in perfused mesenteric vascular beds isolated from Long–Evans Tokushima Otsuka rat (LETO) and Otsuka Long–Evans Tokushima Fatty (OLETF) rats at 8 (8w; a and c) and 25 (25w; b and d) weeks of age. Open and closed bars indicate LETO rats and OLETF rats, respectively. Each bar indicates the mean±s.e.m. for four to five experiments. MPP, mean perfusion pressure.

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