Table 3 Multivariate logistic regression analysis of LVH

From: Subclinical nephrosclerosis is linked to left ventricular hypertrophy independent of classical atherogenic factors

  

Model 1 (unadjusted)

Model 2 (age- and sex-adjusted)

Model 3 (multivariate-adjusted)

Tertiles of %GGS

Number

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Low (0–3.45%)

80

1.0 (Reference)

 

1.0 (Reference)

 

1.0 (Reference)

 

Moderate (3.46–11.76%)

78

5.3 (0.83–103)

0.08

4.3 (0.61–85)

0.15

1.8 (0.22–39)

0.60

High (⩾ 11.77%)

80

15.8 (3.0–291)

<0.01

13.9 (2.64–257)

<0.01

7.0 (1.03–132)

<0.05

  1. Abbreviations: CI, confidence interval; GFR, glomerular filtration rate; LVH, left ventricular hypertrophy; OR, odds ratio; %GGS; percentage of global glomerulosclerosis.
  2. Subjects in the highest tertile of %GGS had a worse risk profile for LVH than did subjects in the lowest tertile, even in the age- and sex-adjusted (Model 2) and multivariate-adjusted models (Model 3). Model 1, unadjusted analysis; Model 2, adjusted for age and sex; Model 3, adjusted for age, sex, systolic blood pressure, history of diabetes mellitus, total serum cholesterol and GFR determined by a radioisotopic technique. The values are ORs and their 95% CI’s versus the lowest tertile.
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