Figure 1
Change in serum aldosterone associated with (a) 5% weight loss and (b) 5 cm2 reduction in thigh intermuscular fat area: differences by baseline metabolic syndrome (MetS) status. Parameter estimates and 95% confidence intervals shown are from a linear-mixed effects model for log aldosterone that included baseline age, sex, race (black/non-black), weight, intervention arm, time since baseline, baseline and within-subject changes in 24-h urinary sodium and potassium excretion, percent weight reduction (or change in thigh intermuscular fat area), baseline MetS status and the interaction between percent weight reduction (or change in thigh intermuscular fat area) and baseline MetS status. The P-value shown is for the interaction.
