Figure 2

Change in diastolic blood pressure (DBP) associated with a 50-mmol per 24 h decrease in sodium excretion: differences by baseline metabolic syndrome (MetS) status. Parameter estimates and 95% confidence intervals shown are from a linear-mixed effects model for DBP that included baseline age, sex, race (black/non-black), weight, intervention arm, time since baseline, baseline and within-subject changes in urinary sodium and potassium excretion and serum aldosterone, percent weight reduction, baseline MetS status, and the interaction between change in sodium excretion and baseline MetS status. The P-value shown is for the interaction between change in sodium excretion and baseline MetS status in this model. A decrease in sodium excretion of 50 mmol per 24 h was approximately the median decrease from baseline to 24 months in the low Na/lifestyle intervention arm.