Figure 2 | Hypertension Research

Figure 2

From: Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats

Figure 2

Myocyte cross-sectional area and expression of fetal-type cardiac genes in the left ventricle of rats in the five experimental groups at 11 weeks of age. (a) Hematoxylin-eosin staining of transverse sections of the LV myocardium. Scale bars, 100 μm. (b) Cross-sectional area of cardiac myocytes determined from sections similar to those in (a). (c, d) Quantitative RT-PCR analysis of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) mRNAs, respectively. The amount of each mRNA was normalized by that of GAPDH mRNA and then expressed relative to the mean value for the CONT group. Data in (b) through (d) are means±s.e.m. (n=6, 6, 11, 11 and 11 rats for the CONT, LVH, Val, VAml and VCil groups, respectively). *P<0.05 vs. CONT group; †P<0.05 vs. LVH group; ‡P<0.05 vs. Val group.

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