Table 2 Cardiac morphological and functional parameters in rats of the five experimental groups at 11 weeks of age

From: Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats

Parameter

CONT

LVH

Val

VAml

VCil

IVST (mm)

1.67±0.05

2.53±0.08a

2.05±0.02a,b

2.05±0.02a,b

2.01±0.02a,b

LVDd (mm)

7.96±0.10

6.26±0.22a

7.33±0.08a,b

7.17±0.10a,b

7.27±0.25a,b

LVPWT (mm)

1.65±0.04

2.52±0.09a

2.02±0.05a,b

2.04±0.02a,b

1.98±0.08a,b

LVDs (mm)

4.28±0.33

2.30±0.44a

3.25±0.19a,b

3.18±0.19a,b

3.32±0.30a,b

LVFS (%)

45.05±2.90

70.03±3.06a

55.24±1.83a,b

55.97±6.33a,b

56.38±2.68a,b

LVEF (%)

82.6±2.2

96.7±0.9a

90.9±1.0a,b

91.7±1.4a,b

92.0±1.6a,b

LV mass (mg)

920±29

1333±49a

1155±38a,b

1079±26a,b

1091±56a,b

RWT

0.41±0.01

0.79±0.06a

0.62±0.01a,b

0.60±0.02a,b

0.50±0.02a,b,c,d

IRT (ms)

33.8±0.9

47.8±0.5a

41.0±2.0a,b

38.4±1.4b

35.4±1.6b,c

DcT (ms)

46.7±1.0

65.5±1.4a

56.9±1.4a,b

55.0±2.5a,b

49.3±1.4b,c,d

Tei index

0.48±0.01

0.66±0.05a

0.59±0.02

0.55±0.01b

0.49±0.02b,c

tau (ms)

22.1±1.5

38.75±2.3a

32.5±4.8a

29.07±1.5a

24.4±0.8b,c

LVEDP (mm Hg)

4.2±0.2

8.0±0.3a

8.0±0.3a

7.0±1.0a

5.7±0.9b,c

LVEDP/LVDd (mm Hg per mm)

0.48±0.02

0.99±0.01a

1.05±0.03a

0.93±0.11a

0.71±0.12b,c

  1. Abbreviations: DcT, deceleration time; IVST, interventricular septum thickness; LV, left ventricular; LVDd, LV end-diastolic dimension; LVDs, LV end-systolic dimension; LVEDP, LV end-diastolic pressure; LVFS, LV fractional shortening; LVEF, LV ejection fraction; LVPWT, LV posterior wall thickness; IRT, isovolumic relaxation time; RWT, relative wall thickness; tau, time constant of isovolumic relaxation. Data are means±s.e.m. (n=6, 6, 11, 11 and 11 for the CONT, LVH, Val, VAml and VCil groups, respectively.
  2. aP<0.05 vs. CONT group.
  3. bP<0.05 vs. LVH group.
  4. cP<0.05 vs. Val group.
  5. dP<0.05 vs. VAml group.