Figure 3 | Hypertension Research

Figure 3

From: Time course of cardiac inflammation during nitric oxide synthase inhibition in SHR: impact of prior transient ACE inhibition

Figure 3

Histological examination of myocardium from rats treated with l-NAME (C+L) (a–d) or enalapril followed by l-NAME (E+L) (e–h) for 0, 3, 7 and 10 days. Myocardium displayed normal histological features in both C+L and E+L at day 0. In both treatment groups, there were 1–2 small foci of infarct as early as day 3 that was characterized by cardiomyocyte loss and increased cellular infiltrate (b, f). The progression of this damage was characterized by increases in size and number of foci of infarction in myocardium from both treatment groups over the course of 10 days. Representative sections stained with Hematoxylin and Eosin, × 100 magnification. Arrowheads point to foci of infarction. A full color version of this figure is available at Hypertension Research journal online.

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