Table 1 Subject Characteristics

From: The impact of tetrahydrobiopterin administration on endothelial function before and after smoking cessation in chronic smokers

 

Smokers (pre)

Smokers (post)

Controls

Overall n/number females

57/31

34/14

15/6

Age (years)

43±6

38±7*

Cigarettes smoked daily (#)

20±13

0±0*

Years smoking (years)

22±8

0±0*

Fagerstrom score (pts)

6±4

0±0*

Carbon monoxide (p.p.m.)

17±10

2±2

3±2*

Serum cotinine (ng ml−1)

191±105

0±0

0±0*

Systolic blood pressure (mm Hg)

120±12

120±14

111±9*

Diastolic blood pressure (mm Hg)

77±8

76±10

73±7

Resting heart rate (b.p.m.)

75±13

69±13

65±12*

Body mass index (kg m−2)

29±7

30±9

28±6

Total cholesterol (mg dl−1)

191±39

190±41

179±34

High density lipoprotein cholesterol (mg dl−1)

54±17

55±15

58±15

Low density lipoprotein cholesterol (mg dl−1)

112±33

112±29

96±27

Triglycerides (mg dl−1)

119±63

129±72

128±118

Augmentation pressure (mm Hg)

6.9±4.8

7.9±4.1

5.7±3.4

Augmentation Index @ HR75 (mm Hg)

19.4±12.2

18.4±10.0

15.7±10.0

Central PWV (m s−1)

7.5±1.6

8.0±2.2

6.5±1.4

Peripheral PWV (m s−1)

9.5±2.1

10.0±2.1

9.5±2.6

  1. Abbreviation: PWV, pulse wave velocity
  2. *indicates significant difference (P<0.05) between smokers and controls at baseline.
  3. indicates significant difference (P<0.05) between smokers pre- and post-smoking cessation.