Figure 4 | Hypertension Research

Figure 4

From: Chronotherapy with conventional blood pressure medications improves management of hypertension and reduces cardiovascular and stroke risks

Figure 4

(Top) Changes from baseline (mm Hg) in office BP measurements (OBPM), 48 h awake (active span) and asleep (nighttime resting span) systolic blood pressure (SBP) means by 160 mg day−1 valsartan ingested upon awakening or at bedtime in patients with grade 1–2 essential hypertension assessed by 48 h ambulatory BP monitoring (ABPM) before and after 12 weeks of timed treatment. Probability values are shown for comparison of effects between the two treatment-time patient groups. (Bottom) Changes from baseline (mm Hg) during the 24 h in SBP after treatment with 160 mg day−1 valsartan ingested either upon awakening or at bedtime. *P<0.05 in BP reduction between the two treatment-time groups. A full color version of this figure is available at the Hypertension Research journal online.

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