Table 2 NAMPT genotypes and allele frequencies in healthy pregnant, gestational hypertension and preeclampsia groups

From: Effects of NAMPT polymorphisms and haplotypes on circulating visfatin/NAMPT levels in hypertensive disorders of pregnancy

Genotype or allele

Health pregnant (n=212, %)

Gestational hypertension (n=181, %)

OR (95% CI)

P values

Preeclampsia (n=208, %)

OR (95% CI)

P values

rs1319501 T>C

       

TT

117 (55)

108 (60)

1.000 (Reference)

141 (68)

1.000 (Reference)

TC

77 (36)

63 (35)

0.886 (0.580–1.354)

0.576

58 (28)

0.625 (0.411–0.951)

0.027a

CC

18 (9)

10 (5)

0.602 (0.266–1.361)

0.235

9 (4)

0.415 (0.179–0.958)

0.034a

T

311 (73)

279 (77)

1.000 (Reference)

340 (82)

1.000 (Reference)

C

113 (27)

83 (23)

0.819 (0.591–1.135)

0.229

76 (18)

0.615 (0.443–0.855)

0.003a

rs3801266 A>G

       

AA

108 (51)

86 (48)

1.00 (Reference)

94 (45)

1.000 (reference)

AG

84 (40)

86 (48)

1.286 (0.850–1.944)

0.232

96 (46)

1.06 (0.68–1.66)

0.184

GG

20 (9)

9 (4)

0.565 (0.244–1.304)

0.177

18 (9)

1.14 (0.66–1.97)

0.924

A

300 (71)

258 (71)

1.000 (Reference)

 

284 (68)

1.000 (Reference)

 

G

124 (29)

104 (29)

0.975 (0.716–1.330)

0.874

132 (32)

1.124 (0.838–1.509)

0.434

  1. Abbreviations: CI, confidence interval; NAMPT, nicotinamide phosphorybosil transferase gene; OR, odds ratio.
  2. aP<0.05 vs. health pregnant group.