Figure 1

cAMP accumulation in CHO cells. cAMP accumulation was determined in the presence of 1 mm 3-isobutyl-1-methylxanthine in hD5F173L-, hD5WT- and empty vector-transfected CHO cells treated with a D1-like receptor agonist, fenoldopam (10−6 m, 30 min) (n=3/group, mean±s.e., in some, error bars are smaller than the symbols, *P<0.05, one-way analysis of variance, Holm–Sidak test). In the absence of D1R, fenoldopam is a D5R agonist.