Figure 5 | Hypertension Research

Figure 5

From: Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse

Figure 5

Effect of Ang II infusion on differentiation of chondrocytes. (a) Accumulation of hypertrophic chondrocytes in cartilage after rib fracture at 2 weeks after rib fracture. N=5 per group. (b–f) Relative mRNA expression of Sox9 (b), Runx2 (c), type X collagen (d), MMP-13 (e) and Ihh (f) in cartilage at 2 weeks after rib fracture. MP-13, matrix metalloproteinase-13; Ihh, Indian hedgehog. Values are expressed as mean±s.e.m. *P<0.05 vs. Saline, **P<0.01 vs. Saline, †P<0.05 vs. Ang II, ††P<0.01 vs. Ang II, #P<0.05 vs. Ang II+Hyd, ##P<0.01 vs. Ang II+Hyd. N=5 per group.

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