Table 3 Characteristics of the patients (Study 3: Valsartan vs. Telmisartan, 8 weeks)
Valsartan | Telmisartan | |||
|---|---|---|---|---|
Pretreatment | Posttreatment | Pretreatment | Posttreatment | |
n (M/F) | 94 (49/45) | 91 (46/45) | ||
Age (years) | 60.7±1.1 | 61.0±1.1 | ||
Body mass index (kg m−2) | 24.2±0.4 | 24.6±0.3 | ||
Waist circumference (cm) | 83.6±1.1 | 85.7±1.1 | ||
Systolic blood pressure (mm Hg) | 143.9±1.1 | 130.9±1.9a | 143.8±1.3 | 133.8±1.7a |
Diastolic blood pressure (mm Hg) | 83.1±0.9 | 75.9±1.4a | 84.2±1.0 | 77.9±1.1a |
Pulse rate (beats min−1) | 70.5±1.0 | 71.2±1.0 | 71.9±0.9 | 72.6±1.1 |
Biochemical data | ||||
Total cholesterol (mg dl−1) | 210.0±3.8 | 205.9±3.6 | 214.7±3.3 | 213.0±3.4 |
HDL cholesterol (mg dl−1) | 62.6±1.8 | 60.4±1.8 | 60.6±1.7 | 58.3±1.8 |
LDL cholesterol (mg dl−1dl) | 121.5±3.4 | 118.4±3.1 | 127.1±3.2 | 127.0±3.3 |
Triglycerides (mg dl−1) | 112 (69–171) | 103 (76–165) | 114 (85–173) | 115 (86–164) |
Glucose (mg dl−1) | 93.3±1.5 | 94.6±1.6 | 93.3±1.5 | 91.2±1.6 |
Insulin (μU ml−1) | 5.5 (3.7–14.3) | 7.4 (3.9–23.1) | 7.4 (4.2–14.2) | 6.9 (4.3–15.1) |
HOMA-R | 1.05 (0.70–1.72) | 1.11 (0.72–1.93) | 1.21 (0.80–1.94) | 1.06 (0.79–1.73) |
Cr (mg dl−1) | 0.65±0.01 | 0.66±0.01 | 0.66±0.01 | 0.67±0.01 |
Estimated GFR (ml min−1 1.73 m−2) | 86.3±1.5 | 85.6±1.6 | 83.9±1.7 | 82.1±1.6 |
