Table 1 Baseline demographic and clinical characteristics of HL and LL controls and patients
HLs | LLs | |||||
---|---|---|---|---|---|---|
Parameters | NHLs | HHLs | NLLs | HLLs | ||
n | 245 | 241 | P-value | 935 | 545 | P-value |
Gender | ||||||
Male | 225 (92%) | 215 (89%) | 836 (90%) | 495 (91%) | ||
Female | 20 (8%) | 26 (11%) | 99 (10%) | 50 (9%) | ||
Clinical characteristics | ||||||
Age (year) | 47.9±12.0 | 48.8±8.1 | NS | 46.6.0±12.7 | 46.5±12.3 | NS |
BMI (kg m−2) | 22.0±5.6 | 23.0±6.3 | NS | 23.7±3.7 | 24.5±2.9 | NS |
SBP (mm Hg) | 115.4±9.7 | 156.5±19.3 | <0.0001 | 115.6±7.0 | 159.8±16.8 | <0.0001 |
DBP (mm Hg) | 72.3±7.6 | 96.8±12.7 | <0.0001 | 75.5±4.8 | 96.2±7.7 | <0.0001 |
MAP (mm Hg) | 86.8±7.4 | 116.5±12.7 | <0.0001 | 88.8±4.9 | 117.4±9.6 | <0.0001 |
Biochemical parameters | ||||||
Total cholesterol, mmol l−1 | — | — | — | 2.9±0.7 | 3.0±1.1 | NS |
Triglyceride, mmol l−1 | — | — | — | 1.2±0.4 | 1.2±0.5 | NS |
Uric acid, mg dl−1 | — | — | — | 4.7±1.0 | 4.7±1.7 | NS |
Glucose, mg dl−1 | — | — | — | 99.5±21.0 | 101.0±22.0 | NS |
Proteinurea | Nil | Nil | — | Nil | Nil | — |
Specific biochemical parameters | ||||||
8-isoPGF2α (pg ml−1) | 3.3±0.9 | 5.8±1.3 | <0.0001 | 2.3±0.6 | 4.8±0.8 | <0.0001 |
Catalase (U ml−1) | 29.7±8.9 | 16.5±4.8 | <0.0001 | 35.8±9.2 | 25.9±8.4 | <0.0001 |
Life style/history | ||||||
Diet (nonveg) | 12% | 23% | — | 15% | 25% | — |
Family history (HT) | None | 73% | — | None | 75% | — |
Alcohol | None | None | — | 6% | 10% | — |
Smoking history | None | None | — | 9% | 12% | — |