Figure 1

CpG dinucleotides and transcription factor-binding sites in the AGT promoter. Nucleotide numbers are relative to the transcription start site. CpG dinucleotides from −483 to +78 are numbered from the 5′ to 3′ ends. A CpG dinucleotide denoted as an unnumbered lollipop was not analyzed in the previous study.23 GR, glucocorticoid receptor; M, methylated CpG; MR, mineralocorticoid receptor; U, unmethylated CpG. A full color version of this figure is available at the Hypertension Research journal online.