Table 3 Weighted mean differences in pulse wave velocity between the ARB treatment and control groups according to the type of drugs in treatment group

From: The impact of angiotensin receptor blockers on arterial stiffness: a meta-analysis

Subgroups

Studies (n)

WMD; 95% CI; P

I2 (P)

baPWV

 Telmisartan

9

−100.82; −145.66 to −55.98; 0.000

96.3% (0.000)

 Losartan

4

−81.30; −204.54 to −41.95; 0.196

96.4% (0.000)

 Valsartan

19

−104.59; −154.01 to −55.18; 0.000

95.7% (0.000)

 Candesartan

4

−139.49; −288.74 to 9.76; 0.067

71.0% (0.016)

 Irbesartan

3

−69.70; −176.80 to 37.40; 0.202

0.0% (0.723)

cfPWV

 Losartan

4

37.02; −122.88 to 48.86; 0.398

92.7% (0.000)

 Valsartan

6

−65.58; −124.84 to −6.32; 0.030

69.0% (0.006)

 Candesartan

3

−3.77; −47.53 to 39.99; 0.866

0.0% (0.559)

  1. Abbreviations: 95% CI, 95% confidence interval; ARB, angiotensin receptor blocker; baPWV and cfPWV, brachial-ankle and carotid-femoral pulse wave velocity; I2, inconsistency index; WMD, weighted mean difference.