Table 4 Weighted mean differences in systolic and diastolic blood pressure between the ARB treatment and control groups according to the types of drugs taken in both groups
From: The impact of angiotensin receptor blockers on arterial stiffness: a meta-analysis
Systolic blood pressure (mm Hg) | Diastolic blood pressure (mm Hg) | |||||
|---|---|---|---|---|---|---|
Groups | Studies ( n) | WMD; 95% CI; P | I2 (P) | Studies (n) | WMD; 95% CI; P | I2 (P) |
Overall | 52 | −0.74; −1.58 to 0.11; 0.086 | 68.9% (0.000) | 52 | −0.58; −1.15 to −0.02; 0.042 | 78.8% (0.000) |
By drugs in treatment group | ||||||
Valsartan | 25 | −0.16; −1.50 to 1.19; 0.821 | 74.1% (0.000) | 25 | −0.71; −1.63 to 0.20; 0.128 | 88.0% (0.000) |
Telmisartan | 8 | −1.12; −1.82 to −0.42; 0.002 | 0.0% (0.911) | 8 | 0.35; −0.10 to 0.80; 0.123 | 0.0% (0.975) |
Losartan | 9 | −1.93; −4.08 to 0.22; 0.078 | 63.1% (0.006) | 9 | −0.68; −1.53 to 0.17; 0.117 | 21.0% (0.256) |
Candesartan | 7 | −1.73; −5.29 to 1.83; 0.340 | 49.7% (0.064) | 7 | −1.07; −3.47 to 1.32; 0.380 | 60.9% (0.018) |
Irbesartan | 3 | 0.51; −2.42 to 3.45; 0.731 | 56.8% (0.099) | 3 | −0.49; −4.26 to 3.27; 0.798 | 62.2% (0.071) |
By drugs in control group | ||||||
ACEI | 9 | −0.92; −2.74 to 0.91; 0.325 | 50.8% (0.039) | 9 | −0.90; −2.41 to 0.62; 0.248 | 57.7% (0.015) |
Placebo | 6 | −3.81; −6.70 to −0.91; 0.010 | 77.2% (0.001) | 6 | −2.65; −3.89 to −1.40; 0.000 | 36.1% (0.166) |
Diuretics | 5 | −1.31; −2.33 to −0.27; 0.013 | 0.0% (0.777) | 5 | −1.49; −3.63 to 0.64; 0.170 | 83.8% (0.000) |
CCB | 20 | 0.51; −0.72 to 1.75; 0.417 | 65.6% (0.000) | 20 | 0.50; −0.23 to 1.23; 0.179 | 79.8% (0.000) |
Beta blocker | 4 | −0.78; −2.88 to 1.32; 0.469 | 0.0% (0.991) | 4 | −2.11; −3.43 to −0.78; 0.002 | 4.4% (0.371) |
Non-RAS | 5 | −2.30; −6.12 to 1.52; 0.238 | 58.3% (0.048) | 5 | −0.73; −2.77 to 1.31; 0.482 | 33.2% (0.200) |
