Table 2 Post irbesartan treatment parameter changes

From: Impact of irbesartan, an angiotensin receptor blocker, on uric acid level and oxidative stress in high-risk hypertension patients

 

Baseline

12 Weeks after irbesartan treatment

P-value

Systolic BP, mm Hg

124±12

122±14

0.618

Diastolic BP, mm Hg

72±7

70±6

0.793

Heart rate, per min

72±11

73±12

0.928

UA, mg dl−1

5.9±1.6

5.5±1.6

0.028

Total cholesterol, mg dl−1

149±17

152±17

0.535

LDL cholesterol, mg dl−1

71±20

72±21

0.642

HDL cholesterol, mg dl−1

46±12

49±13

0.379

Triglyceride, mg dl−1

158±80

149±79

0.261

Fasting blood glucose, mg dl−1

107±24

108±29

0.325

HbA1c, %

6.0±0.8

6.0±0.8

0.521

NT-proBNP, pg ml−1

244±259

225±236

0.386

eGFR, ml min−1

68±15

68±14

0.653

hsCRP, mg ml−1

0.12±0.14

0.09±0.13

0.292

dROMs, U.CARR

354±83

310±65

<0.001

  1. Abbreviations: BP, blood pressure; dROM, derivative of reactive oxygen metabolite; eGFR, estimated glomerular filtration rate; HbA1c, glycohemoglobin A1c; HDL, high-density lipoprotein; hsCRP, high sensitivity C-reactive protein; LDL, low-density lipoprotein; NT-proBNP, N-terminal pro-brain natriuretic peptide; UA, uric acid.
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