Figure 2

Whole-cell K⁺ currents in normal and preeclamptic HUVECs. (a) Representative images of whole-cell K⁺ currents in HUVECs. (b) Current density in normal and preeclamptic HUVECs. N=23, n=48 for NP; N=24, n=52 for PE. (c–e) The effect of BKCa and/or SKCa blocker on whole-cell K⁺ currents in normal and preeclamptic HUVECs. N=20, n=41 for NP; N=21, n=38 for PE. Apamin, a selective SKCa blocker; HUVEC, human umbilical vein endothelial cell; IBTX, a selective BKCa blocker; N, number of participants; n, number of cells; NP, normal pregnancy; PE, preeclampsia. Error bars denote s.e.m. *P<0.05; **P<0.01; ^#P>0.05.