Table 1 Study 1: subject characteristics
Normal gradient crPWV>cfPWV N=528 | Reverse gradient crPWV<cfPWV N=1039 | Significance | |
---|---|---|---|
Age (years) | 62±6 | 69±7 | P<0.001 |
Gender (male/female) | 583/456 | 239/289 | P<0.001 |
Height (m) | 1.67±0.08 | 1.68±0.09 | NS |
Weight (kg) | 71.4±13.7 | 75.3±13.7 | P<0.001 |
Brachial systolic BP (mm Hg) | 122±17 | 135±21 | P<0.001 |
Brachial diastolic BP (mm Hg) | 74±7 | 76±8 | NS |
Pulse pressure (mm Hg) | 48±14 | 58±18 | P<0.001 |
Central systolic BP (mm Hg) | 115±14 | 126±17 | P<0.001 |
Central diastolic BP (mm Hg) | 75±7 | 77±8 | P<0.001 |
Central pulse pressure (mm Hg) | 40±10 | 49±13 | P<0.001 |
Mean arterial pressure (mm Hg) | 88±9 | 93±10 | P<0.001 |
Unaugmented central systolic BP (mm Hg) | 102±11 | 111±12 | P<0.001 |
Unaugmented central pulse pressure (mm Hg) | 27±6 | 34±8 | P<0.001 |
Heart rate (beats per min) | 63±9 | 66±10 | P<0.001 |
Augmentation index (%) | 30±9 | 31±10 | P<0.05 |
Augmentation pressure (mm Hg) | 13±6 | 15±7 | P<0.001 |
Carotid-femoral PWV (m s−1) | 7.5±1.1 | 10.4±2.4 | P<0.001 |
Carotid-radial PWV (m s−1) | 8.7±1.1 | 8.1±1.3 | P<0.001 |
Time-to-reflection (ms) | 78.3±3.6 | 72.2±4.3 | P<0.001 |
Distance to reflection site (cm) | 52.1±8.7 | 71.3±1.6 | P<0.001 |
Total cholesterol (mmol l−1) | 5.4±1.0 | 5.4±1.1 | NS |
Triglycerides (mmol l−1) | 1.4±0.8 | 1.6±0.9 | P<0.01 |