Table 5 Odds ratios of hypertension by weight change since 25 years of age (N=14 635)

From: Relations of body weight status in early adulthood and weight changes until middle age with hypertension in the Chinese population

  

OR (95% CI)

Weight change

No. of cases (%)

Model 1 a

Model 2 b

Model 3 c

<−7.5

154 (16.0)

0.87 (0.70–1.06)

0.85 (0.69–1.05)

0.58 (0.47–0.72)

−7.5 to −2.6

303 (15.0)

0.89 (0.75–1.04)

0.89 (0.75–1.05)

0.77 (0.65–0.91)

−2.5 to 2.5

422 (15.4)

1.00 (reference)

1.00 (reference)

1.00 (reference)

2.6 to 7.5

617 (21.0)

1.53 (1.33–1.76)

1.50 (1.30–1.73)

1.66 (1.43–1.91)

7.6 to 12.5

756 (27.1)

2.09 (1.82–2.40)

2.00 (1.74–2.30)

2.35 (2.03–2.71)

>12.5

1273 (40.0)

3.63 (3.19–4.13)

3.40 (2.98–3.88)

4.36 (3.80–5.01)

P for trendd

 

<0.001

<0.001

<0.001

  1. Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.
  2. aModel 1 adjusted for age and sex.
  3. bModel 2 additionally adjusted for urbanization (urban or rural), education level (primary school or below, junior high school, high school or equivalent or at least some college), smoking status (current smoker or not), drinking status (current drinker or not) and family history of hypertension.
  4. cModel 3 additionally adjusted for BMI at 25 years of age as a continuous variable.
  5. dTrend of linearity over weight change categories was tested by modeling the median values of weight change of each category as a continuous variable in logistic regression model.