Figure 1 | Hypertension Research

Figure 1

From: Reverse electrical remodeling following pressure unloading in a rat model of hypertension-induced left ventricular myocardial hypertrophy

Figure 1

Myocardial remodeling and pressure unloading-induced reverse remodeling. LVH was detected by significantly increased cardiomyocyte diameter (CD) in the weeks 6 and 12 aortic-banded groups (a, b). However, pressure unloading led to a significant reduction of increased CD, indicating regression of LVH (a, b). Furthermore, while myocardial fibrosis proved to be significantly increased in the aortic-banded week 12 group, pressure unloading effectively inhibited the collagen accumulation in the interstitium (a, c). The representative photomicrographs (a) were stained with hematoxylin and eosin and Picrosirius red, respectively. Magnification × 20, scale bar, 50 μm. All values are expressed as the means±s.e.m. *P<0.05 vs. age-matched sham, #P<0.05 vs. aortic-banded week 6, $P<0.05 vs. aortic-banded week 12. A full color version of this figure is available at the Hypertension Research journal online.

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