Table 2 Multivariable linear regression analysis of the association of vascular calcification score and other variables with total BMD (dependent variable)

	Dependent variable
	Total BMD	Cortical BMD	Subcortical BMD	Trabecular BMD
Score of vascular calcifications	−0.354**	−0.028^ns	−0.322*	−0.150^ns
Sex (men/women=1/0)	0.379***	0.312*	0.233°	0.509***
Age, years	−0.068^ns	−0.125^ns	−0.086^ns	0.110^ns
Hypercholesterolemia (yes/no)	−0.019^ns	−0.073^ns	0.063^ns	−0.144^ns
Smoking (yes/no)	−0.140^ns	0.047^ns	−0.144^ns	−0.035^ns
Diabetes mellitus (yes/no)	−0.053^ns	0.043^ns	−0.092^ns	0.037^ns
eGFR, ml min⁻¹ × 1.73 m²	0.063^ns	0.167^ns	0.084^ns	0.027^ns
Normalized plasma total calcium, mg dl⁻¹	0.113^ns	0.068^ns	0.033^ns	0.181^ns
Plasma phosphorus, mg dl⁻¹	0.202^ns	0.242°	0.261°	0.073^ns
Plasma parathyroid hormone, pg ml⁻¹	−0.107^ns	−0.042^ns	−0.117^ns	−0.078^ns
Plasma 25(OH) vitamin D, ng ml⁻¹	0.033^ns	0.028^ns	−0.041^ns	0.033^ns
Treatment with thiazide diuretics (yes/no)	0.075^ns	−0.126^ns	0.118^ns	−0.047^ns
R ²	0.276	0.183	0.277	0.295

*P=0.009, **P=0.002; ***P=0.001; °P<0.05.
Standardized regression coefficient, R² and P-values, ns, not significant (P>0.05).

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