Figure 1 | International Journal of Obesity

Figure 1

From: Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes

Figure 1

Effects of I3C on F4/80 expression in epididymal adipose tissue (AT), × 200 magnification (a) and × 400 magnification (b), in animals fed different diets for 12 weeks (C, control diet; HF, high-fat diet; HFI, high-fat diet+intraperitoneally administered I3C). Immunohistochemistry detected a macrophage-specific antigen (F4/80) in epididymal AT from high-fat diet-induced obese mice. The black arrows showed abundant macrophages within AT. Macrophages were observed both near blood vessels and among large adipocytes. The scale bar represents 100 μm.

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