Table 1 MiRNAs differentially expressed between Control (con) and obesogenic diet (OB) fetal skeletal muscle

From: Maternal obesity downregulates microRNA let-7g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development

MicroRNA

Con

OB

Log2 (OB/Con)

P-value

Hsa-let-7g

23 060±106

21 379±433

−0.12

0.066

Hsa-miR-381

2367±46

3306±93

0.50

0.002

Bta-miR-376d

6991±178

4835±583

−0.52

0.091

Hsa-let-7b

63±2

83±5

0.38

0.04

Hsa-miR-1306

36±1

30±2

−0.32

0.10

  1. Three muscle samples of fetuses at an average body weight within each group were used for microRNA microarray analyses (n=3) based on all known miRNAs of human, rat, mouse, cattle and sheep.