Table 2 Methylation profiles in children from non-obese parents at the DMRs of imprinted genes

From: Newborns of obese parents have altered DNA methylation patterns at imprinted genes

Baseline methylation percentage in children from non-obese parents

 

MEG3-IG

MEG3

MEST

NNAT

PEG3

PLAGL1

SGCE/PEG10

 

%

s.e.

%

s.e.

%

s.e.

%

s.e.

%

s.e.

%

s.e.

%

s.e.

CpG 1

47.4

0.9

51.1

1.4

45.6

0.5

61.5

0.8

36.0

0.4

62.8

1.3

50.2

0.5

CpG 2

42.5

0.9

67.9

1.6

46.4

0.5

56.0

0.8

38.5

1.2

61.2

1.3

49.0

0.5

CpG 3

60.2

0.9

73.4

1.1

45.8

0.5

53.0

0.7

38.3

0.4

61.3

1.3

50.9

0.5

CpG 4

53.0

1.1

70.5

1.2

48.5

0.6

  

35.3

0.5

59.1

1.2

47.2

0.5

CpG 5

  

75.5

0.8

    

41.0

0.4

58.6

1.0

49.4

0.7

CpG 6

  

78.3

1.0

    

35.8

0.5

56.2

1.1

53.0

0.5

CpG 7

  

83.0

0.6

    

35.9

0.4

    

CpG 8

  

74.6

0.9

    

33.1

0.6

    

CpG 9

        

39.8

0.4

    

CpG 10

        

41.2

0.6

    

Mean

50.8

0.7

71.8

1.0

46.6

0.5

56.9

0.8

37.5

0.3

59.8

1.1

50.0

0.5

  1. Abbreviations: MEG3, maternally expressed gene 3; MEST, mesoderm-specific transcript; NNAT, neuronatin; PEG3, paternally expressed gene 3; PLAGL1, pleiomorphic adenoma gene-like 1; SGCE/PEG10, epsilon sarcoglycan and paternally expressed gene 10.
  2. The estimated means of methylation percentages for children born from non-obese parents are presented for each DMR, by the individual CpG site studied. The calculated mean for each DMR is shown at the bottom line.
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