Table 1 Clinical data for cohort 1

From: Adipose tissue morphology predicts improved insulin sensitivity following moderate or pronounced weight loss

Measure

Before weight loss

After weight loss

 

Hyperplasia (n=43)

Hypertrophy (n=57)

P-value

Hyperplasia

Hypertrophy

P-value

Age, years

40±7

37±7

0.01

−

−

−

BMI, kg m−2

36±4

37±5

0.46

34±4

34±5

0.47

Body fat, %

51±11

52±13

0.82

46±10

47±13

0.68

Waist circumference, cm

110±9

114±12

0.08

104±8

108±12

0.04

Waist-to-hip ratio

0.94±0.05

0.97±0.07

0.013

0.92±0.05

0.96±0.07

0.0058

Insulin, mU l−1

10±4

17±9

<0.0001

9±7

12±6

0.052

Glucose, mmol l−1

5.8±2.4

5.6±1.0

0.67

5.5±1.7

5.3±1.1

0.60

HOMAIR

2.7±1.7

4.4±3.1

0.003

2.3±1.8

2.9±2.1

0.14

Fat cell volume, pl

697±106

895±105

<0.0001

−

−

−

Morphology value, pl

−89±74

115±82

<0.0001

−

−

−

  1. Abbreviations: BMI, body mass index; HOMAIR, homeostasis model assessment-estimated insulin resistance. Values are mean±s.d. They were compared by unpaired t-test.
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