Table 2 Adipose tissue characteristics of NW (n=22) and obese (n=11) pregnant women in T1 and T3
Characteristic | NW | P -valuea | Obese | P -valuea | NW | Obese | P-valueb | ||
|---|---|---|---|---|---|---|---|---|---|
T1 | T3 | T1 | T3 | Change from T1 to T3 | |||||
Cellularity | |||||||||
Adipocyte diameter (μm) | 79.0±11.4 | 86.7±8.8 | <0.01 | 91.2±18.9 | 86.8±15.8 | NS | 7.7±11.0 | –4.4±16.2 | <0.05 |
Adipocyte volume (pl) | 354.6±114.7 | 455.7±103.8 | <0.01 | 600.3±208.4b | 542.3±175.2 | NS | 101.0±122.6 | –57.9±189.0 | <0.05 |
Adipocyte number (1010) | 5.53±2.06 | 5.27±1.66 | NS | 10.27±5.74c | 11.32±4.38c | NS | –0.26±1.99 | 1.05±6.24 | NS |
<50 μm (%) | 19.7±15.0 | 17.3±10.2 | NS | 24.1±19.1 | 26.8±16.4 | NS | –2.5±12.6 | 2.7±17.6 | NS |
50–100 μm (%) | 56.0±18.4 | 44.9±15.3 | <0.05 | 21.1±6.4c | 23.4±7.0c | NS | –11.1±17.1 | 2.3±8.7 | <0.05 |
100–150 μm (%) | 24.1±15.2 | 37.6±14.4 | <0.01 | 53.7±22.4c | 48.6±18.6 | NS | 13.5±16.8 | –5.1±16.9 | <0.01 |
>150 μm (%) | 0.13±0.19 | 0.26±0.46 | NS | 1.1±1.0c | 1.2±1.6b | NS | 0.1±0.4 | 0.1±1.3 | NS |
Density | |||||||||
Macrophages (no. mm–2)c | 0.2±0.2 | 0.2±0.2 | NS | 0.1±0.2 | 0.1±0.0 | NS | 0.0±0.2 | –0.1±0.2 | NS |
Mast cells (no. mm–2)c | 0.8±0.4 | 0.8±0.5 | NS | 0.9±1.1 | 0.8±0.8 | NS | 0.1±0.5 | –0.1±0.6 | NS |
Vessels (%) | 0.8±0.8 | 0.9±1.2 | NS | 0.6±0.4 | 0.7±0.6 | NS | 0.2±0.8 | 0.2±0.3 | NS |
In vitro release | |||||||||
Glycerol (nmol g–1 TG) | 980.2±331.8 | 1522.2±831.2 | <0.05 | 1252.7±530.3 | 2019.0±1285.9 | <0.05 | 542.0±913.0 | 766.3±1129.3 | NS |
Glycerol (nmol per 104 cells) | 3.0±1.2 | 6.1±3.1 | <0.001 | 6.1±2.6c | 9.4±6.7 | NS | 3.1±3.1 | 3.3±6.2 | NS |
IL-6 (24-h, ng l–1g–1)c | 563.5±572.6 | 386±234.0 | NS | 285.5±101.5 | 352.3±89.3 | NS | –177.5±657.2 | 66.8±177.9 | NS |
TNF-α (24-h, ng l–1g–1)c | 4.9±8.6 | 3.3±2.1 | NS | 3.5±2.7 | 3.5±2.0 | NS | –1.6±9.4 | 0.0±2.3 | NS |
Adiponectin (24-h, μg l–1g–1) | 176.8±52.1 | 124.7±41.8 | 0.001 | 155.7±68.2 | 137.1±43.3 | NS | –52.1±43.3 | –18.6±41.2 | <0.05 |
