Figure 2 | International Journal of Obesity

Figure 2

From: Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery

Figure 2

Correlation between miRNome and metabolic profiles. The heat map is generated from the Pearson correlation coefficient values between circulating microRNA expression and metabolite levels using a two-way clustering method. The horizontal axis shows all detectable circulating microRNAs, whereas the vertical axis exhibits altered plasma, urinary and hepatic metabolites following RYGB. The color bar next to the metabolites indicates metabolic functions (amino acid metabolism, lipid metabolism and ketone body metabolism, glycolysis and glycogenolysis, TCA cycles, microbial activity, nucleic acid metabolism, muscle metabolism and vitamin metabolism) of the metabolites. MicroRNAs, which are significantly altered by RYGB surgery, are shown in yellow (upregulated) and blue (downregulated), respectively. SHAM n=4, RYGB n=4. Keys: PAG, phenylacetylglycine; TMAO, trimethyalmine-N-oxide; TCA, tricarboxylic acid.

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