Figure 2 | International Journal of Obesity

Figure 2

From: Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans

Figure 2

Clustering of prostaglandins with markers of biological processes. (a) PCA plot showing separation of WT, HFD fed and ob/ob mice based on prostaglandins and gene expression markers. (b) Loadings plot for PCA analysis shown above. Arrows show directions of contributions by: (1) Lipolytic markers, (2) adipogenic markers, (3) Insulin-sensitivity markers, (4) De novo lipogenic markers, (5) T-cell markers, and (6) Macrophage markers. (c) NEATmaps of transcriptomic and prostaglandin data. N=8 mice per group, for PCA analyses. N=6 mice per group for clustering analyses. C57Bl/6 females, 16 weeks of age.

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