Table 4 Associations of clock gene expression with the expression of inflammatory genes in SAT

From: Regulation of the clock gene expression in human adipose tissue by weight loss

		TLR pathway					Total macrophage marker	M1 macrophage markers			M2 macrophage markers
		NFKB1	NFKBIA	NLRP3	TLR2	TLR4	EMR1	CCL2	CD11c	TNFA	CD163	IL10	MRC1
BMAL1	CID1	0.362**	0.371**	0.345*		0.355*	0.312*						0.352*
	CID2	0.318*		0.305*	0.511**		0.530**		0.290*		0.362*		0.426**
CLOCK	CID1	0.596**	0.548**	0.412**	0.309*		0.381**		0.459**	0.360*	0.466**		0.484**
	CID2	0.347*	0.462**		0.378**	0.451**					0.496**		0.447**
CRY1	CID1	0.573**	0.517**	0.416**	0.293*	0.316*	0.310*	0.296*	0.313*		0.528**		0.588**
	CID2	0.649**	0.576**	0.502**	0.441**	0.474**		0.428**			0.669**	0.420**	0.697**
CRY2	CID1	0.547**	0.751**	0.535**		0.495**	0.537**		0.345*	0.344*	0.425**		0.535**
	CID2	0.657**	0.624**	0.414**	0.444**	0.331*	0.422**				0.615**		0.639**
DBP	CID1		0.543**			0.331*	0.403**	−0.282*
	CID2	0.319*	0.685**			0.441**	0.290*		0.300*
NR1D1	CID1	0.489**	0.514**	0.438**									0.369**
	CID2	0.447**	0.443**	0.372**	0.498**	0.418**	0.342*				0.455**		0.416**
PER1	CID1						0.385**
	CID2		0.398**
PER2	CID1	0.568**	0.607**	0.498**			0.437**				0.370**		0.449**
	CID2	0.562**	0.579**	0.345*	0.318*	0.454**					0.340*		0.353*
PER3	CID1	0.578**	0.777**	0.640**	0.301*		0.491**		0.528**	0.491**	0.668**		0.690**
	CID2	0.700**	0.782**	0.364*	0.401**	0.555**	0.370*				0.534**	0.290*	0.652**
TEF	CID1
	CID2		0.437**			0.460**							0.378**

Abbreviations: SAT, subcutaneous adipose tissue; TLR, Toll-like receptor. Correlations of gene expression levels before (CID1) and after the weight loss (CID2) are presented. Only significant correlation links (r-values) are shown. *P<0.05, **P<0.01 without correction for multiple testing. Correlations significant after false-discovery rate correction are in bold.

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Table 4 Associations of clock gene expression with the expression of inflammatory genes in SAT

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