Table 1 Pre-treatment characteristics

From: Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR−/−.Leiden mice

 

t=0

t=9 Weeks

 

Chow

LFD

HFD

Body weight (g)

26.3±0.3a

32.3±0.9b

39.0±1.0c

Plasma cholesterol (mM)

5.4±0.1a

16.1±2.0b

16.8±1.1b

Plasma triglycerides (mM)

1.0±0.0a

2.6±0.4b

2.6±0.2b

Blood glucose (mM)

6.5±0.1a

6.5±0.4a

8.5±0.2b

Plasma insulin (ng ml−1)

1.1±0.1a

2.2±0.4b

5.2±0.5c

  1. All data are mean±s.e.m. Means in a row with superscripts without a common letter differ significantly (P<0.05).
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