Table 2 The association between alleles of Taq1A and the weight of adults with a BMI in the healthy range and who are overweight
Sample | Age | N | BMI A1/A1 | BMI A1/A2 | BMI A2/A2 | % A1/A1 | % A1/A2 | % A2/A2 | |
|---|---|---|---|---|---|---|---|---|---|
Spitz et al.28 | Control Obese BMI >30 Matched to cancer patients in another study | 62 Years 64 Years | 139 37 | 27.5 NS | 26.1 | 31.2% 58.3% P<0.002 | 68.8% 41.7% | ||
Thomas et al.37 | Male BMI <27 Female BMI <25 Not obese Obese (BMI higher than 27 or 25) | 42 Years | 383 | NA | 20.7% 20.6% | 50.0% 52.7% NS | 29.3% 26.7% | ||
Thomas et al.29 | (BMI males <27, females BMI <25) Not obese Obese (BMI higher than 27 or 25) | 44.1 Years 50.0 Years | 506 484 | 25.0 | 24.8 NS | 24.6 | 19.3% 21.6% | 48.8% 54.9% p<0.03 | 31.9% 23.4% |
Southon et al.38 | Women Leaner BMI 22.5 Heavier BMI 36.1 | 54.3 Years 55.6 Years | NA | 0% 0% | 65% 40% NS | 35% 60% | |||
Epstein et al.30 | Smokers | 43.5 Years | 88 | 26.7 NS | 27.5 | 3.4% | 43.2% | 53.4% | |
Fang et al.31 | Normotensive Hypertensive | 38.1 Years 41.7 Years | 141 133 | 25.6 | 25.1 NS | 25.5 | 17.9% | 49.6% | 32.4% |
Morton et al.35 | Nonsmokers Former smokers Current smokers If BMI >30 | 55–74 Years | 442 | Odds ratio 1.28 | BMI >30 1.40 P<0.02 | 1.00 | 4.4% | 29.6% | 65.9% |
Nisoli et al.32 | Control BMI 23.7 Obese BMI 42.7 | 31.2 Years 46.9 Years | 54 71 | 23.6 42.1 NS | 23.8 43.1 | 1.9% 8.4% | 24.4% 26.8% NS | 73.7% 64.8% | |
Epstein et al.33 | Smokers Nonobese BMI <30 Obese BMI >30 | 23.4 Years 29.3 Years | 45 29 | 26.3 NS | 29.0 | ||||
Davis et al.39 | Control BMI 22.4 Obese BMI 39.1 | 33.5 Years 36.3 Years | 59 51 | NA | 1.7% 5.9% | 32.2% 43.1% NS | 66.1% 51.0% | ||
Stice et al.19 a | Females BMI 28.6 | 20.4 Years | 43 | 28.5 NS | 27.9 | 25.6% | 74.4% | ||
Epstein et al.69 | BMI >30 | 42 Years | 26 | NA | 42.3% | 57.7% | |||
Chen et al.36 | Controls BMI 21.9 Obese/overweight BMI 29.3 | 36.5 Years 42.3 Years | 105 122 | NA | 33.4% 67.0% P<0.001 | 66.6% 33.0% | |||
Roth et al.22 | Lean adults | 25 Years | 583 | 18.2 | 19.1 NS | 19.2 | 2.6% | 27.6% | 69.8% |
Athanasoulia et al.34 | Patients with prolactinomas | 53.1 Years | 44 | 26.6 NS | 25.9 | 6.8% | 40.9% | 52.3% | |
Hardman et al.23 | Representative sample of mothers | Age NA | 2513 | 24.7 | 25.0 NS | 24.8 | 3.7% | 30.4% | 65.8% |
Yokum et al.24 | Females | 20.9 Years | 34 | Average BMI 28.2 No details but BMI did not differ with allele | |||||
