Table 1 Anthropometric and metabolic characteristics of the overall cohort and subgroups (IR and non-IR subjects) that were employed for the fingerprinting (group1) and the validation (group 2) studies
Group 1 | Overall cohort (n=60) | IR (n=30) | Non-IR (n=30) | Significance |
|---|---|---|---|---|
Males/females | 30/30 | 15/15 | 15/15 | NS |
Age (years) | 8.56±1.70 | 8.77±1.87 | 8.35± 1.72 | NS |
BMI-SDS | 4.75±1.40 | 4.99±1.45 | 4.50±1.33 | NS |
Fasting glucose (mg dl−1) | 91.88±5.43 | 92.80±5.51 | 90.97±5.28 | NS |
Fasting insulin (μU ml−1) | 15.35± 10.95 | 21.78±12.32 | 8.93±2.57 | P<0.001 |
HOMA index | 3.49±2.40 | 4,97±2.62 | 2.01±0.60 | P<0.001 |
HbA1c (%) | 5.40±0.35 | 5.38±0.42 | 5.40±0.35 | NS |
AUC-glucose (mg dl−1) | 248.50±33.28 | 262.50±34.94 | 232.35±22.68 | P<0.001 |
AUC-insulin (μU ml−1) | 220.05±145.67 | 329.61±117.18 | 98.31±33.88 | P<0.001 |
WBISI | 1.11±0.65 | 0.60±0.18 | 1.70±0.47 | P<0.001 |
Uric acid | 4.85±1.15 | 4.96±1.34 | 4.74± 0.92 | NS |
Total cholesterol (mg dl−1) | 163.45±33.52 | 162.83±36.03 | 164.07±31.41 | NS |
LDL cholesterol (mg dl−1) | 99.46±29.49 | 98.08±30.35 | 100.85±29.05 | NS |
HDL cholesterol (mg dl−1) | 47.06±12.48 | 43.24±11.01 | 50.87±12.88 | P<0.05 |
VLDL cholesterol (mg dl−1) | 17.17±12.00 | 21,61±14.71 | 12.72±5.96 | P<0.01 |
Triglycerides (mg dl−1) | 86.09±60.49 | 109.28±74.56 | 63.67±29.89 | P<0.01 |
Group 2 | Overall cohort (n=100) | IR (n=50) | Non-IR (n=50) | Significance |
|---|---|---|---|---|
Males/females | 50/50 | 25/25 | 25/25 | NS |
Age (years) | 7.83±2.70 | 9.09±2.06 | 5.25±1.99 | P<0.001 |
BMI-SDS | 5.17±2.19 | 5.10±2.39 | 5.25±1.99 | NS |
Fasting glucose (mg dl−1) | 92.66±7.36 | 95.82±7.82 | 89.50±5.29 | P<0.001 |
Fasting insulin (μU ml−1) | 14.59±6.96 | 20.04±5.23 | 9.13±3.13 | P<0.001 |
HOMA index | 3.38±1.72 | 4.74±1.32 | 2.02±0.72 | P<0.001 |
HbA1c (%) | 5.40±0.39 | 5.52±0.43 | 5.29±0.31 | P<0.01 |
AUC-glucose (mg dl−1) | 256.42±40.61 | 271.74±43.02 | 238.20±28.75 | P<0.001 |
AUC-insulin (μU ml−1) | 203.47±113.84 | 282.61±92.72 | 106.74±34.50 | P<0.001 |
WBISI | 3.38±1.95 | 1.94±0.49 | 5.09±1.62 | P<0.001 |
Uric acid | 4.46±0.85 | 4.66±0.79 | 4.26±0.87 | P<0.05 |
Total cholesterol (mg dl−1) | 159.47±30.54 | 162.53±31.60 | 156.41±29.46 | NS |
LDL cholesterol (mg dl−1) | 96.36±25.44 | 98.32±27.09 | 94.39±23.78 | NS |
HDL cholesterol (mg dl−1) | 47.44±12.86 | 45.59±11.79 | 49.30±13.71 | NS |
VLDL cholesterol (mg dl−1) | 15.54±8.51 | 18.60±8.69 | 12.48±7.19 | P<0.001 |
Triglycerides (mg dl−1) | 77.71±42.56 | 93.02±43.47 | 62.41±35.97 | P<0.001 |
