Table 1 Clinical and biochemical characteristics of women with PCOS by the NICHD criteriaa and their controls
From: Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity
Cases, n=145 | Controls, n=687 | P-value | |||||||
|---|---|---|---|---|---|---|---|---|---|
95% CI | 95% CI | ||||||||
Mean | Lower | Upper | s.d. | Mean | Lower | Upper | s.d. | ||
Waist circumference (cm) | 84.9 | 82.3 | 87.5 | 16.5 | 78 | 77.2 | 78.9 | 11.2 | 7.4E−6 |
Waist-hip ratio | 0.84 | 0.83 | 0.85 | 0.08 | 0.8 | 0.79 | 0.81 | 0.1 | 9.2E−6 |
BMI (kg m−2) | 26.5 | 25.5 | 27.6 | 6.6 | 23.7 | 23.4 | 24.1 | 4.4 | 9.1E−6 |
HOMA insulin resistance (IR) | 1.25 | 1.13 | 1.37 | 0.73 | 0.98 | 0.95 | 1.01 | 0.41 | 3.5E−5 |
HOMA beta cell function | 108.7 | 103 | 114.4 | 35.6 | 97.5 | 95.7 | 99.3 | 24.6 | 5.5E−4 |
HOMA insulin sensitivity | 98.5 | 92.2 | 104.9 | 39.8 | 114.7 | 112 | 117.4 | 36.7 | 2.3E−5 |
Glucose (mmol l−1) | 5.0 | 4.9 | 5.1 | 0.4 | 4.9 | 4.86 | 4.94 | 0.5 | 1.8E−2 |
Insulin (mU l−1) | 9.7 | 8.8 | 10.6 | 5.8 | 7.6 | 7.4 | 7.8 | 3.2 | 3.7E−5 |
SHBG (nmol l−1) | 56.5 | 49.7 | 63.3 | 42 | 65.9 | 63.4 | 68.4 | 33.5 | 1.5E−2 |
Testosterone (nmol l−1) | 2.9 | 2.7 | 3.0 | 1.0 | 1.6 | 1.57 | 1.63 | 0.4 | 1.2E−34 |
Luteinizing hormone (U l−1) | 10.8 | 7.7 | 13.8 | 18.8 | 6.1 | 5.6 | 6.6 | 6.9 | 4.9E−3 |
Systolic blood pressure (mmHg) | 122.0 | 119.2 | 124.5 | 13.8 | 118.6 | 117.7 | 119.5 | 11.7 | 6.0E−3 |
Diastolic blood pressure (mmHg) | 77.1 | 75.6 | 79.5 | 11.7 | 74 | 73.2 | 74.8 | 10.3 | 1.0E−3 |
Total cholesterol (mmol l−1) | 5.0 | 4.8 | 5.2 | 1.0 | 4.8 | 4.7 | 4.9 | 0.9 | 1.1E−2 |
LDL cholesterol (mmol l−1) | 3.0 | 2.8 | 3.1 | 0.9 | 2.75 | 2.7 | 2.8 | 0.9 | 1.2E−2 |
HDL cholesterol (mmol l−1) | 1.5 | 1.5 | 1.6 | 0.4 | 1.7 | 1.67 | 1.73 | 0.4 | 8.9E−4 |
Triglycerides (mmol l−1) | 1.1 | 1.0 | 1.2 | 0.6 | 0.86 | 0.83 | 0.89 | 0.4 | 8.1E−6 |
