Figure 2
From: Neuromodulation of orexin neurons reduces diet-induced adiposity
Acute pharmacosynthetic activation of orexin neurons increases SPA in female and male Cre::hM3Dq mice (N=21). Behavioral activity in large activity chambers (MedAssociates; St. Albans, VT) 4 h after an injection of CNO (5 mg/kg; black bars) or vehicle (0 mg/kg; saline; white bars), 5 h into the Light Cycle. Time spent moving (a), chow intake (b), and fecal boli (c) in female (n=13) and male (n=8) mice. *P<0.05, **P<0.01, ***P<0.001.
