Figure 6
From: Neuromodulation of orexin neurons reduces diet-induced adiposity
SPA and EE following acute pharmacosynthetic inhibition in Female Cre::hM4Di mice (n=6). Time spent moving in large activity chambers (MedAssociates; St. Albans, VT) 4 h after an injection of CNO (5 mg/kg; black boxes) or vehicle (veh; saline; white circle) and 15 min before dark cycle onset (a) or 5 h into the Light Cycle (b); (N=4). SPA (c) and EE (d) 2 h post injection in a home-cage environment (Promethion™; SableSystem, Reno, NV). Total chow intake (e) and fecal boli (f) during the 12 h dark cycle (N=4). *P<0.05, **P<0.01, ***P<0.001.
