Figure 5

Basal plasma concentrations of appetite-related hormones (a: active ghrelin (AG), b: GLP-1, c: CCK, d: PYY and e: insulin) over time in all participants, males and females. Results presented as estimated marginal means±s.e.m. Symbols denote significant differences from baseline in all participants: ***P<0.001 and *P<0.05, males: ^&&&P<0.001, ^&&P<0.01 and ^&P<0.05, and females: ^###P<0.001 and ^#P<0.05. CCK, cholecystokinin; GLP-1, glucagon-like peptide-1; PYY, total peptide YY; WL, weight loss.