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The role of bacterial biofilm in persistent infections and control strategies
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  • Published: 01 April 2011

The role of bacterial biofilm in persistent infections and control strategies

  • Li Chen1 &
  • Yu‐mei Wen1 

International Journal of Oral Science volume 3, pages 66–73 (2011)Cite this article

  • 11k Accesses

  • 221 Citations

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Abstract

Bacterial biofilms can be viewed as a specific type of persistent bacterial infection. After initial invasion, microbes can attach to living and non‐living surfaces, such as prosthetics and indwelling medical devices, and form a biofilm composed of extracellular polysaccharides, proteins, and other components. In hosts, biofilm formation may trigger drug resistance and inflammation, resulting in persistent infections. The clinical aspects of biofilm formation and leading strategies for biofilm inhibitors will be discussed in this mini‐review.

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Authors and Affiliations

  1. Key Laboratory of Medical Molecular Virology of Ministry of Education and Ministry of Public Health, Shanghai Medical School of Fudan University, Shanghai, 200032, China

    Li Chen & Yu‐mei Wen

Authors
  1. Li Chen
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  2. Yu‐mei Wen
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Correspondence to Li Chen.

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Cite this article

Chen, L., Wen, Y. The role of bacterial biofilm in persistent infections and control strategies. Int J Oral Sci 3, 66–73 (2011). https://doi.org/10.4248/IJOS11022

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  • Received: 26 February 2011

  • Accepted: 13 March 2011

  • Published: 01 April 2011

  • Issue date: 01 April 2011

  • DOI: https://doi.org/10.4248/IJOS11022

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Keywords

  • biofilm
  • persistent infection
  • 3A remedies

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International Journal of Oral Science (Int J Oral Sci)

ISSN 2049-3169 (online)

ISSN 1674-2818 (print)

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