Table 1 Percentages of reduction of Enterococcus faecalis biofilms by alexidine alone and combined with NAC after 1 min of exposure: mean (SD)

From: Antimicrobial activity of alexidine alone and associated with N-acetylcysteine against Enterococcus faecalis biofilm

 

E. faecalis ATCC 29212

E. faecalis D1

ALX concentrations/%

Alone

Combined with NAC

Alone

Combined with NAC

2

E

E

E

E

1

E

E

E

E

0.5

E

E

E

E

0.25

E

E

E

E

0.125

E

E

E

E

0.062 5

E

E

E

E

0.031

E

E

E

E

0.015 6

E

99.75 (0.18)a,1

99.92 (0.13)a,2

99.70 (0.39)a,1,2

0.007 8

99.46 (0.57)1

97.22 (2.00)b,2

99.50 (0.48)b,1

99.23 (0.50)b,1

  1. ALX, alexidine; E: eradication, 100% bacterial kill; NAC, N-acetylcysteine, 100 mg⋅mL−1.
  2. Read vertically, the same letter shows differences not statistically significant.
  3. Read horizontally, the same number shows differences not statistically significant.
  4. E. faecalis ATCC 29212: ALX 0.007 8% vs. ALX 0.007 8%+NAC, P<0.001.
  5. E. faecalis D1: ALX 0.015 6% vs. ALX 0.015 6%+NAC, P=0.104; ALX 0.007 8% vs. ALX 0.007 8%+NAC, P=0.163.
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