Table 2 Genes identified as up-regulated or down-regulated by RNA-Seq and microarray analysis

From: Identification of the involvement of LOXL4 in generation of keratocystic odontogenic tumors by RNA-Seq analysis

Regulation

Protein location

Biological functions

Synonyms

RNA-Seq

Microarray

Up

Extracellular

Related to ECM formation and degradation

LOXL4

1.586 5

3.174 3

  

Other functions

SUSD2

5.498 1

1.918 6

   

NPB

2.444 6

1.974 1

  

Related to osteoblast and osteoclast

TCTA

1.817 8

1.504

  

Related to ECM formation and degradation

LARP6

2.004

1.735 9

  

Related to immune functions

ZBTB32

102.989 1

1.608 2

 

Intracellular

Other functions

HCST

5.070 3

1.994 1

   

HCP5

1.957 2

2.169 9

   

UCHL1

1.830 2

1.636 9

   

MBNL3

1.730 4

1.573 9

   

ZNF671

1.694 1

1.503 2

   

ADCY4

1.599 1

3.774 6

   

RDH5

1.595 3

1.550 1

Down

Intracellular

Related to cell proliferation and apoptosis

KIT

4.258 5

4.790 4

   

TNFRSF25

3.598 5

1.562

   

RGS12

1.796 5

1.527 2

   

RICTOR

1.721 9

1.859 1

  

Other functions

GLRX

1.822 3

1.661 3

   

MAG12

1.798 4

1.514 9

   

FEM1B

1.585 7

1.672 7

   

IQSEC2

1.572 4

1.593 7

  1. ECM, extracellular matrix; LARP6, La ribonucleoprotein domain family, member 6; LOXL4, lysyl oxidase-like 4; RNA-Seq, RNA sequencing; TCTA, T-cell leukemia translocation-associated gene.