Figure 4

Expression of genes involved in four metabolic pathways in 24-h S. mutans biofilms. (a) Adhesion/biofilm formation; (b) EPS synthesis; (c) carbohydrate uptake; (d) acid tolerance. Fold upregulation or downregulation is depicted in relation to the unsupplemented base medium (control) containing 0.58% glucose. Error bars represent the 95% confidence interval. Statistical significance is denoted by asterisks (n=10). EPS, extracellular polysaccharide.