Figure 2
From: Bivalent histone modifications during tooth development
The spatialtemporal expression of histone methylation transferase EZH2 and SET7 during tooth germ development. Protein signals of EZH2 and SET7 were detected by immunohistochemistry in mouse tooth germ from E13.5 to P3. (a) EZH2 was expressed in the enamel epithelium, stellate reticulum and dental papilla in E13.5 and E15.5 respectively and was expressed in both the dental papilla and enamel organ at E17.5 and P0. At P3, EZH2 was expressed in the odontoblast layer and inner enamel epithelium. (b) qPCR results showed that gene level of EZH2 was expressed in the whole dental germ in bell stage, early enamel formation stage and enamel formation stage. (c) SET7 showed significant positive expression in dental papilla E17.5, P0 and P3. (d) qPCR results showed that gene level of SET7 was expressed in the whole dental germ in bell stage, early enamel formation stage and enamel formation stage. qPCR, quantitative polymerase chain reaction.
