Figure 2

Change in α diversity and bacterial taxonomic profiles in plaque microbiota with or without CPC treatment. (a) The α diversity in the control group exhibited a significant increase from Baseline to Day 21, whereas that in the CPC group remained stable. These changes resulted in the profound differences in richness and in the Shannon index between the CPC and control groups at Day 21 underlying the distinct clinical symptoms between the two groups at Day 21. (b) Comparison of bacterial taxonomic profiles of the CPC and control groups from Baseline to Day 21 at the genus level. **P<0.01. CPC, cetylpyridinium chloride; NS, not significant.