Figure 4

Distinct temporal dynamics of 25 taxa from Baseline to Day 21 between the CPC and control groups. (a) Between-treatment comparisons of bacterial abundance at each time point. The abundance change for each taxon was calculated as the abundance at Day 21 deducted from that at baseline. (b) The temporal changes in relative abundance for these 25 taxa were significantly (adjusted P<0.05, Wilcoxon rank-sum test) different between subjects in the CPC and control group. The dots were classified into three groups: red, gingivitis enriched; green, gingivitis depleted; blue, neutral. Bacterial classification was based on comparing the microbial profiles of the control group at Baseline and Day 21. CPC, cetylpyridinium chloride.